issue 31// vol 46 Milestone achieved by Canadian news // no. 5 researchers for potential COVID-19 vaccine » Tested and proven highly effective in ferrets The lasting lockdown Illustration by Athena Little Tania Arora Staff Writer Sn the global pandemic entered the spotlight, researchers all over the world are trying every means to come up witha vaccine for the COVID-19 virus. Canadian researchers are part of the global effort. The team of researchers at The University of Saskatchewan's Vaccine and Infectious Disease Organization- International Vaccine Centre (VIDO- InterVac) announced a possible vaccine candidate and are moving towards clinical trials. Vaccines are developed using living organisms to help the body fight the trouble caused by a pathogen (disease- causing organism). The vaccine candidate developed by the research organization is proved to be “highly effective” in the pre- clinical trials when tested on ferrets. According to The University of Saskatchewan’s VIDO-InterVac, “To evaluate the effectiveness of the vaccine, the ferrets received two immunizations c¢ before being exposed to SARS-CoV-2, the virus that causes COVID-19. The vaccine- induced a strong immune response generated neutralizing antibody and decreased viral infection in the upper respiratory tract to almost undetectable levels.” Project head Dr. Darryl Falzarano stated that they “are excited by these results and are continuing to develop our vaccine towards regulatory approval.” After this animal trial, the research organization will be moving to human clinical trials this fall. Before this announcement, other research organizations also claimed success from animal trials, including Quebec- based biotech company Medicago Inc., and IMV Inc.—another Quebec company. Although the vaccine to begin human trials is by CanSino Biologics—a Chinese company in collaboration with Canada’s National Research Council. The vaccine has proven to have positive results when tested on more than 100 subjects in Wuhan. After this animal trial, the research organization will be moving to human clinical trials this fall. > BC officially in longest state of emergency in province's history Lauren Gargiulo Contributor Bes Columbia's current state of emergency is now the longest in the province’s history. BC Premier John Horgan extended the emergency for another two weeks on Wednesday, as BC residents start preparing for phase two of the province’s restart plan. In phase two, health services including elective surgery have been restarted, as well as physical therapy, massage therapy, dentistry, and other medical services. According to the province's plan, phase two means that the government is “asking people to stay close to home and avoid any travel between communities that are not essential.” If transmission rates of COVID-19 continue to decline, people can begin travelling throughout BC during phase three, which is estimated to start between June and September. Despite BC having the lowest mortality rate in a jurisdiction in Canada, the United States, and Europe with more than 2,500 positive cases and over 150 deaths, Horgan is not looking to end the state of emergency in two weeks time. Although BC is on track with its restart plan, Horgan told reporters on May 27 that there “is likely no end in sight” and is expecting BC’s state of emergency to last longer than the current time of 12 weeks. The provincial government can extend the period of a state of emergency up to 14 days at a time. The longest state of emergency previously was due to the 2017 wildfire season which lasted for 10 weeks from July 7 to Sept. 15. Ina response about the provincial state of emergency extension Minister of Public Safety and Solicitor General Mike Farnworth said the government “is committed to supporting people and businesses for the long road ahead.” As restaurants and retail businesses start re-opening, “we must work together [...] in a way that keeps our communities and loved ones safe in the weeks and months to come.” Horgan states in the same document. Businesses like hair salons, restaurants, and massage therapists can operate on a 50 percent capacity—with many businesses requiring both patrons and employees to wear masks. BC legislature will be returning on June 22, with MLAs working both from the BC legislature in Victoria and from home Horgan said. “But at the end of the day, Photo of John Horgan via Province of British Columbia on Flickr debates will take place, votes will be cast, and democracy will be well served.”